Trial By Error

Category: functional motor disorder

  • A Letter Seeking a Correction in FMD Physiotherapy Paper

    I have recently written about a trial of an intervention for functional motor disorder (FMD) that had null results for its primary outcome—physical function as rated by the SF-36. The study–“Specialist Physiotherapy for functional motor disorder in England and Scotland (Physio4FMD): a pragmatic, multicentre, phase 3 randomised controlled trial,” published by The Lancet Neurology—had some…

  • Null Results in Physiotherapy Trial for Functional Motor Disorder

    It must be tough for investigators when a major study seeking to assess the effectiveness of an intervention for a challenging condition yields null results. That’s what happened in 2019 with a trial of rituximab for ME/CFS, published in Annals of Internal Medicine. Findings from earlier research had suggested that rituximab, a drug used to…