David Putrino on New Nature Study of Long Covid Immune Profiling

By David Tuller, DrPH

I’ve posted two past interviews with David Putrino (here and here) about long Covid, ME/CFS, and related issues. Dr Putrino, a neuroscientist and physical therapist, is director of rehabilitation innovation at the Mt Sinai Health System in New York. Early in the pandemic, he began seeing patients with prolonged symptoms following acute bouts of Covid-19. He has worked closely in the past few years with Yale immunobiologist Akiko Iwasaki. This week they published a major study in Nature called “Distinguishing features of Long COVID identified through immune profiling,” in which they tested blood from those without and without long Covid and reported significant differences in multiple parameters. Dr Putrino and I recently discussed the study’s findings, what they mean for treatment, and upcoming plans to assess whether similar patterns are seen in ME/CFS patients as well as those who report prolonged symptoms after a covid vaccine.